| # |
Item Name |
Clinical Application |
Key Functions |
| 1 |
BDNF |
Neurological |
To promote the survival, growth, maintenance, and structural adaptation of nerve cells (neurons). |
| 2 |
Angiopoietin-2 |
Angiogenesis |
To regulate the formation, maturation, and stability of blood vessels by binding to the Tie2 receptor on endothelial cells. |
| 3 |
HGF |
Cell Proliferation, Organ repair |
To regulate cell growth, cell motility (movement), and morphogenesis (tissue shape formation) by binding to and activating the c-Met receptor tyrosine kinase. |
| 4 |
M-CSF (CSF-1) |
Proliferation and Differentiation |
To control the survival, proliferation, and differentiation of cells belonging to the mononuclear phagocyte lineage, specifically monocytes and macrophages. |
| 5 |
PDGF-AA |
Cell Proliferation (Mitogenesis); Cell Migration |
Potent mitogen that stimulates the growth, division, and directed migration (chemotaxis) of specific cells, particularly those of mesenchymal and neuroectodermal origin. |
| 6 |
PDGF-BB |
Angiogenesis; Wound Healing and Remodeling |
To stimulate the growth, division, and movement of mesenchymal cells—such as fibroblasts, smooth muscle cells, and glial cells. |
| 7 |
SCF (Stem Cell Factor) |
Hematogenesis, Mass Cell Regulation |
Is to act as a vital cytokine that binds to the c-Kit receptor, regulating the survival, proliferation, differentiation, and migration of stem cells and precursor cells. |
| 8 |
FGF-Basic (FGF-2) (13-FGF) |
Cell Proliferation and Differentiation; Angiogenesis, Wound Healing |
To stimulate cell proliferation, survival, and differentiation across a wide variety of cell types. |
| 9 |
VEGF |
Angiogenesis, Cell Survival |
To stimulate the formation of new blood vessels, a process known as angiogenesis. |
| 10 |
FGF-7 (FGF) |
Keratinocyte growth factor; Tissue Repair |
To stimulate the growth, proliferation, and differentiation of epithelial cells; Paracrine Signaling. |
| 11 |
IL-6 |
Acute Phase Response, Immune Cell Maturation, Fever induction |
A multifunctional cytokine (a signaling protein) whose primary function is to act as a central coordinator of the immune and inflammatory responses, bridging innate and adaptive immunity. |
| 12 |
IL-18 |
Autoimmune and Inflammatory Responses |
To act as a pro-inflammatory cytokine that stimulates innate immunity and induces the production of interferon-gamma in collaboration with Interleukin-12. |
